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Nick Nolte, Susan Sarandon, Peter Ustinov, Kathleen Wilhoite, Gerry Bamman ... see more see more... , Margo Martindale , Zack O'Malley Greenburg , James Rebhorn , Ann Hearn , Maduka Steady , Mary Wakio , Don Suddaby , Charles R. Altman , Billy Amman , Lamont Arnold , Kathryn Aronson , Becky Ann Baker , Noah Banks , Angus Barnett , Todd Bella , Jeremy Beyer , Eliot Brinton , William Cameron , Amelia Campbell , Mary Schmidt Campbell , Susan Chapek , Nancy Chesney , Raina Clifford , Richard Cordery , Connie Cranden , Daniel W. D'Arcy , Elizabeth Daily , Tia Delaney , Anthony di Leo Jr. , David Doepken , Ann Dowd , Jennifer Dundas , Nora Dunfee , Nona Gerard , Mary Pat Gleason , Sandy Gore , Michael Haider , Mack Hegyes , Zahra Ilkanipour , Justin Isfeld , Aaron Jackson , Rachel Jones , Lianne Kressin , Eric Kunkle , Paul Lazar , Laura Linney , Annie Loeffler , Peter Mackenzie , Keiko McDonald , Ann McDonough , David McFadden , Christine Merriman , April Merscher , John Mowod , Marie Nugent-Head , Michael O'Neill , Lamar Olivis , Ayub Ommaya , Vladimir Padunov , Nicolas Petrov , Carmen Piccini , Barbara Poitier , Matthew Pyeritz , Keith Reddin , Joyce Reehling , Julie Marie Remele , La Tanya Richardson , C. Alex Roberts , Helena Ruoti , David Shiner , Ryonosuke Shiono , Rocco Sisto , Neri Kyle Tannenbaum , Shirley Tannenbaum , Ryan Thomas , William Thunhurst Jr. , Berta Van Zuiden , Colin Ward , Nicholas Wiese , Cristin Woodworth , Brad Einhorn , John Lyons , James Merrill

Susan Sarandon and Nick Nolte give brilliant performances as parents trying to save the life of their son in George Miller's harrowing and heartbreaking Lorenzo's Oil. Based on a true story, the film ... read more read more...begins as bright young Lorenzo (Zack O'Malley Greenburg) is leading a pleasant life on the Comoro Islands. But things start to go wrong with him -- he collapses, he raves, and he loses his hearing -- so his concerned parents, Augusto (Nick Nolte) and Michaela Odone (Susan Sarandon), take him to a doctor. The diagnosis is a death warrant; they are told that Lorenzo has been diagnosed with adrenoleukodystrophy (ALD), an rare and incurable nerve disease that is always fatal. When Augusto and Michaela are told to be patient as they watch their son sink further into the debilitating illness, they take matters into their own hands and start their own investigation of the disease. Using rapeseed oil, they find their own treatment for ALD. ~ Paul Brenner, Rovi

Flixster Users

76% liked it

14,355 ratings

Critics

96% liked it

24 critics

PG-13, 2 hr. 16 min.

Directed by: George Miller

Release Date: December 30, 1992

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DVD Release Date: April 6, 2004

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Stats: 720 reviews

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Flixster Reviews (720)


  • August 17, 2011
    There's nothing more horrible than watching an innocent young child suffer in agony. In this heart-gripping drama, we follow two desperate parents (Nick Nolte and Susan Sarandon) as they struggle to find a cure for their son, who has fallen victim to a rare disease known as ALD. ... read moreFine performances by everyone in the cast, and in particular by Zack O'Malley, who does some of the best acting I've ever seen by someone of his age. You're truly enveloped by the pain that he goes through, which often makes it an uncomfortable watch. Seldom have I felt so engaged as to the outcome of a character's fate. And I can imagine it must be even more compelling to those who are parents themselves. A powerful story altogether, that despite some tendencies to drag, will leave you affected in one way or another.
  • May 11, 2011
    A great true story, but it's so boring as a film. I had to watch this in a class I had once, and I just couldn't get into it, it was dull. I'd only recommend this to real die hard drama fans who love real life stories played realistically. Overall, it's pretty good, but could ... read morehave been more exciting.
  • May 18, 2010
    Emotionally harrowing film of a dedicated and persistent couple's struggle to find help for their son when he falls victim to a terminal illness. Intensely real performance by Susan Sarandon and a strong one from Nick Nolte although his accent while accurate for the character mak... read morees it difficult to understand him occasionally. Beautifully true supporting performances but it is hard to watch what Lorenzo has to go through. A shattering experience at times but worthwhile.
  • May 13, 2007
    Criminally underseen and astonishingly powerful.
  • November 21, 2006
    Extraordinary true-life story of two devoted parents who, discovering that their young son has the fatal disease ALD, set out to find a cure despite having no medical knowledge.
  • August 23, 2011
    An emotionally draining examination of possibly the most relentless and heartless disease I've ever heard of, Lorenzo's Oil is well wrought, and most definitely worth watching, due largely in part to the fine performances and educatory stance the film takes. It may frustrate you,... read more but it will undoubtedly affect you.
  • February 7, 2011
    A true story about two determined parents who fight to find a cure for their son Lorenzo who has been diagnosed with a rare terminal illness. I found the movie quite boring sometimes when talking about the technical scientific parts of the disease but other times I found myself f... read moreilled with tears during emotional and heartwarming moments. This movie was very inspiring. However, it could have been a lot better. For one thing, I felt like I was listening to Tommy Pickles' baby gurgling the whole time which was very annoying and distracted me. (This is because Elizabeth Daily played Lorzenzo's heavy breathing. She is also the voice of Tommy Pickles on the Nickelodeon TV show "Rugrats.") Also, sometimes the movie was so technical, it would appeal to someone with a scientific mind and lose people who have less interest in the science and more in the relationships. The acting was really good in this movie and I was very impressed with Zack O'Malley Greenburg's acting. He must have been QUITE a child actor or maybe he really did have a disease. He also spoke different languages! Wow. There was also a slightly heavy-handed scene where the father falls down the stairs and starts tearing at his shirt. This was bizarre and concerning but maybe a parent really would act like that if he knew his son would probably die and there wasn't much he could do about it. The best part of this movie was seeing the love that Lorenzo's parents had for him, and watching his mother Michaela reading to him and talking to him as a human being, not a vegetable, even though he was incapacitated and couldn't respond without blinking his eyes and moving his pinky finger.
  • July 5, 2009
    A very depressing yet incredibly good look at the father that discovered Lorenzo's Oil the medicine that helps kids and people in general that are afflicted with the terrible disease a.l.d. This is a insperational film of one set of parents that defy all the odds and just wont ta... read moreke no for an answer about their child. when alot of parents unfortunatly wouldve given up. A very moving film.
  • May 9, 2009
    Depressing and simple but good acting.
  • June 12, 2007
    A profound and inspirational real-life story about the strength of a family who dares to ask questions and take action when their child is faced with a terminal illness. impeccable casting and performance. this moved me to tears more than once.

Critic Reviews


Stefan Birgir Stefansson
July 5, 2008
Stefan Birgir Stefansson, sbs.is

perhaps the most melodramatic movie ever

Emanuel Levy
February 14, 2007
Emanuel Levy, EmanuelLevy.Com

It takes time to get over Nick Nolte's "wrong" accent, but Susan Sarandon gives a marvelous performance in the George Miller-directed, fact-based drama about a family torn by the degenerative disease ... Full Review

Betty Jo Tucker
June 6, 2004
Betty Jo Tucker, ReelTalk Movie Reviews

Filmdom's most powerful movie about parental concern carried to the max. Full Review

Ken Hanke
December 29, 2002
Ken Hanke, Mountain Xpress (Asheville, NC)

Okay weeper.

Frederic and Mary Ann Brussat
August 21, 2002
Frederic and Mary Ann Brussat, Spirituality and Practice

The true story of two loving parents who fashion a miracle to save the life of their son afflicted with an orphan disease. Full Review

James Sanford
August 14, 2002
James Sanford, Kalamazoo Gazette

Slightly heavy-handed, but mostly effective.

Chris Hicks
January 1, 2000
Chris Hicks, Deseret News, Salt Lake City

The real knockout here, however, is Sarandon, who is absolutely riveting. She's every bit as wrenching, touching and fulfilling as the film itself. Full Review

Owen Gleiberman
September 7, 2011
Owen Gleiberman, Entertainment Weekly

Click to read the article Full Review

March 26, 2009
Variety

Click to read the article Full Review

Janet Maslin
May 20, 2003
Janet Maslin, New York Times

Click to read the article Full Review

Critic ratings and reviews powered by RottenTomatoes.com

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Lorenzo's Oil Trivia


  • Laura Linneys film career began with a part in what film ?  Answer »
  • Mr. Ustinov played opposite both Susan Sarandon and Nick Nolte in which one of these dramas?   Answer »
  • Susan Sarandon won an Oscar for her role in Lorenzo's Oil ?  Answer »
  • Lorenzo's Oil is a 1992 drama film directed by George Miller. It is based on the true story of Augusto and Michaela Odone, two parents in a relentless search for a cure for their sons...  Answer »

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