I have to agree with the first post. Bruce Willis in Armaggedon and Russell Crowe in Gladiator are definitly the saddest for me. I was also sad when V died in V for Vendetta, but I saw it coming, which made it easier.
1)the father in 'Life is beautiful'
2)Leons death in 'Leon- The Professional'
3)Monica Potter in 'Patch Adams '
4)Kate Winslet in 'Finding Neverland '
5)Jenny in 'Forrest Gump'
6)Every time one of his sons dies (especially Heath Ledger) in 'The Patriot'
7)Haley Joel Osment in 'Pay it Forward'
8)Macaulay Culkin in 'My Girl'
9)Jack in 'Titanic'
10) Eric Bana in 'Troy'
and a couple of my favs have already been mentioned
1)mel gibson in Braveheart
2)John Coffey in Green Mile
3)The end of 'The Notebook '
Gia (Angelina Jolie)
Ghost (Patrick Swayze)
The Green Mile (Michael Clarke Duncan)
City Of Angels (Meg Ryan)
Beaches (Barbara Hershey)
My Girl (Macaulay Culkin)
E.T. (even though he came back lol)
Set It Off (Queen Latifah)